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File:Anaplastic astrocytoma - p53 - very high mag.jpg

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Summary

Description
English: Very high magnification micrograph of an anaplastic astrocytoma.p53 immunostain.

The typical features are present:

  • Marked nuclear atypia.
  • Elongated nuclei (consistent with derivation from an astrocyte ).
  • Mitoses.
  • Fine fibrillary processes (consistent with a glial cell population).
  • Cytoplasmic staining of atypical cells with GFAP.
  • p53 immunohistochemical stain positivity.
  • High proliferative rate based on Ki-67 staining.
  • Low mag.
    Low mag.
  • Intermed. mag.
    Intermed. mag.
  • High mag.
    High mag.
  • Very high mag.
    Very high mag.
  • GFAP. Very high mag.
    GFAP. Very high mag.
  • Ki-67. High mag.
    Ki-67. High mag.
Source Own work
Author Nephron

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current02:52, 21 November 2010Thumbnail for version as of 02:52, 21 November 20104,272 × 2,848 (6.21 MB)Nephron{{Information |Description={{en|1=Very high magnification micrograph of an '''anaplastic astrocytoma'''.p53 immunostain. The typical features are present: *Marked nuclear atypia. *Elongated nuclei (

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