Ammonium salicylate

Ammonium salicylate
Names
	IUPAC name Ammonium 2-carboxyphenolate
Identifiers
CAS Number	528-94-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	10265;
ECHA InfoCard	100.007.678
EC Number	208-444-9;
PubChem CID	54697583;
CompTox Dashboard (EPA)	DTXSID30883424;
	InChI InChI=1S/C7H6O3.H3N/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);1H3 Key: BOFZOTMTKBQRAB-UHFFFAOYSA-N;
	SMILES C1=CC=C(C(=C1)C(=O)O)[O-].[NH4+];
Properties
Chemical formula	C7H9NO3
Molar mass	155.153 g·mol−1
Appearance	colorless powder
Solubility in water	soluble
Hazards
	GHS labelling:
Pictograms
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Ammonium salicylate is a chemical compound with the chemical formula NH₄C₆H₄(OH)COO.^[1]

Synthesis

The effect of ammonia solution on salicylic acid in an inert atmosphere:

NH₃ + C₆H₄(OH)COOH → NH₄C₆H₄(OH)COO

Physical properties

Ammonium salicylate forms colorless crystals that are highly soluble in water and ethanol.^[2]^[3] The compound decomposes at 213°C.

Uses

The compound is commonly used in several industries, such as pharmaceuticals, cosmetics, and agriculture.^[4]^[5]

As a drug, it is used in cases of topical skin diseases, relief of various muscle pains and as a component of several medications. Under exposure to light it discolors with the release of ammonia. It easily discolors iron compounds, and it forms a slightly acidic solution in water.^[6]^[7]

References

^ Air and Water Pollution Annual Report. Department of Commerce, National Bureau of Standards, National Measurement Laboratory. 1958. p. 187. Retrieved 15 January 2025.
^ Digest of Comments on The Pharmacopoeia of the United States of America and The National Formulary for the Calendar Year Ending December 31 ... Treasury Department, Public Health and Marine-Hospital Service of the U.S. 1911. p. 166. Retrieved 15 January 2025.
^ National Institutes of Health Bulletin. U.S. Government Printing Office. 1910. p. 62. Retrieved 15 January 2025.
^ "Ammonium Salicylate". Cymer Chemicals. Retrieved 15 January 2025.
^ Heising, Leonard F. (1954). Review of the Ammonia Industry and Its Application to North Dakota. U.S. Department of the Interior, Bureau of Mines. p. 59. Retrieved 15 January 2025.
^ Stedman, Thomas Lathrop (1899). Twentieth Century Practice: Infectious diseases. W. Wood. p. 97. Retrieved 15 January 2025.
^ Perry, Dale L. (19 April 2016). Handbook of Inorganic Compounds. CRC Press. p. 32. ISBN 978-1-4398-1462-8. Retrieved 15 January 2025.

[1] Air and Water Pollution Annual Report. Department of Commerce, National Bureau of Standards, National Measurement Laboratory. 1958. p. 187. Retrieved 15 January 2025.

[2] Digest of Comments on The Pharmacopoeia of the United States of America and The National Formulary for the Calendar Year Ending December 31 ... Treasury Department, Public Health and Marine-Hospital Service of the U.S. 1911. p. 166. Retrieved 15 January 2025.

[3] National Institutes of Health Bulletin. U.S. Government Printing Office. 1910. p. 62. Retrieved 15 January 2025.

[4] "Ammonium Salicylate". Cymer Chemicals. Retrieved 15 January 2025.

[5] Heising, Leonard F. (1954). Review of the Ammonia Industry and Its Application to North Dakota. U.S. Department of the Interior, Bureau of Mines. p. 59. Retrieved 15 January 2025.

[6] Stedman, Thomas Lathrop (1899). Twentieth Century Practice: Infectious diseases. W. Wood. p. 97. Retrieved 15 January 2025.

[7] Perry, Dale L. (19 April 2016). Handbook of Inorganic Compounds. CRC Press. p. 32. ISBN 978-1-4398-1462-8. Retrieved 15 January 2025.

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