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Draft:Amaka Offiah

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Professor
Amaka C. Offiah
Image of Amaka Offiah
Amaka Offiah
Born
Cynthia Nwamaka Mbamali

Edinburgh, Scotland, UK
EducationIntercalated Bachelor of Science

Bachelor of Medicine and Bachelor of Surgery

Doctor of Philosophy
OccupationPaediatric Radiologist
ChildrenTwo
Medical career
InstitutionsUniversity of Sheffield & Sheffield Children's Hospital, Great Ormond Street Hospital London, Oldchurch Hospital Romford
Sub-specialtiesPaediatric musculoskeletal imaging
ResearchPhysical child abuse and skeletal dysplasias

Amaka C. Offiah is Professor of Paediatric Musculoskeletal Imaging at the University of Sheffield (TUOS) [1] and Honorary Consultant Paediatric Radiologist at Sheffield Children’s Hospital. [2]

Early Life

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Born in Edinburgh, the first of six children to Nigerian parents of Igbo origin, Professor Ernest Ikechukwu Mbamali (the third Medical Director of The National Orthopaedic Hospital, Kano) [3] and chemist, Dr Gladys Enuma Mbamali (nee Agbakoba), Offiah's early education was at Gascoyne Cecil Junior School in Hatfield and then at the Convent of Saint Clotilde, Lechlade Manor.

Education

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Offiah moved to Nigeria at around age 12 attending St Louis Secondary School, Bompai, Kano. She gained an Intercalated BSc from the University of Ibadan, before qualifying as a doctor at Ahmadu Bello University Zaria. She worked at Oldchurch Hospital, Romford, where she obtained her Membership of the Royal College of Physicians of London. It was while training in Sheffield to obtain membership of the Royal College of Radiologists that she developed her interest in the radiological diagnosis of inflicted injury (child abuse), thus going on to specialise in paediatric radiology. She later completed a PhD at University College London/Institute of Child Health and then joined the TUOS as a HEFCE Clinical Senior Lecturer and Sheffield Children’s NHS Foundation Trust as an Honorary Consultant Paediatric Radiologist, integrating her clinical practice with her research interests. [4]

Career and Leadership

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As of 2025, Offiah is one of the few Black (African/Afro-Caribbean) female professors of medicine in the UK. [5] She has worked as an academic at the TUOS [1] and an Honorary Consultant Paediatric Radiologist at Sheffield Children's Hospital [2] since 2009. Her research focuses particularly on child abuse and skeletal dysplasias and she has published over 230 papers [6] and four international/national guidelines, two being related to child abuse. [7][8]

Offiah holds the distinction of being the first female, first person of colour and first paediatric radiologist to be awarded the Royal College of Radiology Roentgen Professorship[9] and in 2021, became the first female and first person of colour to serve as Managing Editor for the journal Pediatric Radiology. [10]

Offiah Chairs the ESPR Child Abuse Task Force [11] and The Skeletal Dysplasia Group for Teaching and Research. [12]

Offiah is an advocate for equality, diversity, and inclusion, being TUOS's Faculty of Health Director of Wellbeing, Equality, Diversity & Inclusion, [13] Chair of the University's Race Equality Delivery Group, the Sheffield lead for the Generation Delta project [14], which seeks to lay a foundation to increase the number of black female professors in the United Kingdom and a member of both the Medical Research Council's Black in Biomedical Research Advisory Group [15] and the Equality, Diversity and Inclusion Committee of the Royal College of Radiologists [16] In 2024, the University of Sheffield was successful in its application for a Bronze Race Equality Charter Award under the leadership of Co-Chairs Offiah and Professor Susan Fitzmaurice.

Offiah is on the Board of Trustees of the (Sheffield) Children's Hospital Charity [17] and A Rare Cause. [18]

Research

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Offiah has focused her research on imaging techniques for suspected child abuse and skeletal dysplasias, with an emphasis on distinguishing between children with fragile bones prone to fractures and children with healthy bones who may have been abused. Her work centres on optimising imaging methods, developing techniques to differentiate between brittle and normal bones, studying mechanisms of accidental injury in children, and establishing normative data for the paediatric musculoskeletal system, including through post-mortem imaging. [19] Among her research outputs, she has reported on neonatal osteomyelitis, [20] abnormal vertebral segmentation in humans, [21] and assessed the role of muscle MRI to detect specific patterns of muscle involvement in disorders with spinal rigidity due to various gene mutations. [22] Her radiological phenotyping of a child with symptoms of hypothyroidism but normal thyroid hormone levels contributed to the identification of the first de novo mutation in the thyroid hormone receptor alpha gene in humans. [23] Offiah’s research in the field of child abuse has contributed to uniformity across Europe regarding how these children are imaged and thus to improving safeguarding of vulnerable children. [24] Her article on abusive head trauma [25] is one of Offiah's three child abuse-related articles that are in the top 50 most cited articles published in the first 50 years of existence of the journal Pediatric Radiology. [26] In addition to guidelines for investigating child abuse, Offiah has contributed her radiology expertise to international guidelines for Fibrous Dysplasia/McCune-Albright Syndrome (FD/MAS)[27] and achondroplasia. [28]

Awards and honours

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  • 2013 – RCR Roentgen Professor [9]
  • 2015 – BIR/Bayer Make it Better Award, British Institute of Radiology [29]
  • 2015 – BMJ Award Highly Commended Imaging Team, BMJ Publishing Group [30]
  • 2022 – ESPR Jacques Lefebvre Lecture "Reverse radiology: diagnosis of skeletal dysplasias in the era of whole exome sequencing, artificial intelligence and drug trials" [31]

Bibliography

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Selected books

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  • Fetal and Perinatal Skeletal Dysplasias: an Atlas of Multimodality Imaging 2nd Edition (2024) ISBN 978-1003166948
  • Paediatric Radiology Rapid Reporting (2024) ISBN 978-3031482540

Selected articles

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  • Shalof, H., Chong, R.S., Rigby, A., Offiah, A.C. In children under two years of age, does the bone health index value differ between those with and without osteogenesis imperfecta? Bone 196, 116013 (2025). https://doi.org/10.1016/j.bone.2025.117467
  • Klein, W.M., Offiah, A.C., Kvist, O., Rosendahl, K. On-call or not on-call, what difference does it make in paediatric radiology? Insights Imaging 16, 73 (2025). https://doi.org/10.1186/s13244-025-01948-0
  • Paddock, M., Johnson, P.C., Staley, A., Halliday, K., Offiah, A.C. The impact of sedation on the quality of initial skeletal surveys performed for suspected physical abuse in children: a comparative two-centre audit. Clin Radiol 79, e1057–e1063 (2024). https://doi.org/10.1016/j.crad.2024.04.012
  • Offiah, A.C., Atalabi, O.M., Epelman, M., Khanna, G. Disparities in paediatric radiology research publications from low- and lower middle-income countries: a time for change. Pediatr Radiol 54, 468–477 (2024). https://doi.org/0.1007/s00247-023-05762-y
  • Offiah, A.C. Current and emerging artificial intelligence applications for pediatric musculoskeletal radiology. Pediatr Radiol 52, 2149–2158 (2022). https://doi.org/10.1007/s00247-021-05130-8
  • Thodberg, H.H., Thodberg, B., Ahlkvist, J., Offiah, A.C. Autonomous artificial intelligence in pediatric radiology: the use and perception of BoneXpert for bone age assessment. Pediatr Radiol 52, 1338–1346 (2022). https://doi.org/10.1007/s00247-022-05295-w
  • Shalof, H., Dimitri, P., Shuweihdi, F., Offiah, A.C. Which skeletal imaging modality is best for assessing bone health in children and young adults compared to DXA? A systematic review and meta-analysis. Bone 150, 116013 (2021). https://doi.org/10.1016/j.bone.2021.116013
  • Tong, L., Pooranawattanakul, S., Gopal-Kothandapani, J.S. et al. Comparison of prevalence and characteristics of fractures in term and preterm infants in the first 3 years of life. Pediatr Radiol 51, 86–93 (2021). https://doi.org/10.1007/s00247-020-04817-8
  • Andronikou, S., Kraft, J.K., Offiah, A.C., et al. Whole-body MRI in the diagnosis of paediatric CNO/CRMO. Rheumatology 59, 2671–2680 (2020). https://doi.org/0.1093/rheumatology/keaa303
  • Hemke, R., Herregods, N., Jaremko, J.L., et al. Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis: ESSR-ESPR points to consider. Eur Radiol 30, 5237–5249 (2020). https://doi.org/10.1007/s00330-020-06807-8
  • Martin, A., Paddock, M., Johns, C.S. et al. Avoiding skull radiographs in infants with suspected inflicted injury who also undergo head CT: “a no-brainer?”. Eur Radiol 30, 1480–1487 (2020). https://doi.org/10.1007/s00330-019-06579-w
  • Mikolajewicz, N., Bishop, N., Burghardt, A.J., “et al.” HRpQCT Measures of Bone Microarchitecture Predict Fracture: Systematic Review and Meta-Analysis J Bone Miner Res, 35, 2020, https://doi.org/10.1002/jbmr.3901.
  • Fawaz F. Alqahtani, Nicola J. Crabtree, Paul A. Bromiley, Timothy Cootes, Penny Broadley, Isla Lang, Amaka C. Offiah. Diagnostic performance of morphometric vertebral fracture analysis (MXA) in children using a 33-point software program, Bone, 133, 2020, https://doi.org/10.1016/j.bone.2020.115249.
  • Alshamrani, K., & Offiah, A.C. Applicability of two commonly used bone age assessment methods to twenty-first century children. Eur Radiol 30, 504 (2020). https://doi.org/10.1016/j.crad.2019.08.029
  • Alshamrani, K., Messina, F. & Offiah, A.C. Is the Greulich and Pyle atlas applicable to all ethnicities? A systematic review and meta-analysis. Eur Radiol 29, 2910–2923 (2019). https://doi.org/10.1007/s00330-018-5792-5

References

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  1. ^ a b "Offiah, Amaka, Professor". www.sheffield.ac.uk. 2025-02-06. Retrieved 2025-02-06.
  2. ^ a b "Dr Amaka Offiah". Sheffield Children’s NHS Foundation Trust. Retrieved 2025-02-06.
  3. ^ https://nohkano.gov.ng/past-medical-directors/
  4. ^ CraigPolson (2023-10-31). "Meet Professor Amaka Offiah – Saluting our Sister as part of Black History Month". Sheffield Children’s NHS Foundation Trust. Retrieved 2025-02-06.
  5. ^ "Medicine – Black Female Professors Forum". 2025-05-04.
  6. ^ "Scopus Offiah, Amaka C."
  7. ^ Mankad, Kshitij; Sidpra, Jai; Mirsky, David M.; Oates, Adam J.; Colleran, Gabrielle C.; Lucato, Leandro T.; Kan, Elaine; Kilborn, Tracy; Agrawal, Nina; Teeuw, Arianne H.; Kelly, Patrick; Zeitlin, Deborah; Carter, Jamieson; Debelle, Geoff D.; Berger, Rachel P. (2023-05-01). "International Consensus Statement on the Radiological Screening of Contact Children in the Context of Suspected Child Physical Abuse". JAMA Pediatrics. 177 (5): 526–533. doi:10.1001/jamapediatrics.2022.6184. ISSN 2168-6211. PMID 36877504.
  8. ^ "The radiological investigation of suspected physical abuse in children". www.rcr.ac.uk. Retrieved 2025-02-06.
  9. ^ a b "The Roentgen Professorship | The Royal College of Radiologists". www.rcr.ac.uk. Retrieved 2025-02-06.
  10. ^ Offiah, A. C. (2022-11-01). "Month 12 musings of a managing editor". Pediatric Radiology. 52 (12): 2243–2244. doi:10.1007/s00247-022-05542-0. ISSN 1432-1998. PMID 36287233.
  11. ^ "Child Abuse". ESPR. Retrieved 2025-02-06.
  12. ^ "Committee of Management | Skeletal Dysplasia Group". www.skeletaldysplasiagroup.org.uk. Retrieved 2025-02-06.
  13. ^ "Faculty leadership". www.sheffield.ac.uk. 2024-09-17. Retrieved 2025-02-06.
  14. ^ "Generation Delta".
  15. ^ "MRC Black in Biomedical Research Advisory Group".
  16. ^ "EDI Committee | The Royal College of Radiologists". www.rcr.ac.uk. Retrieved 2025-02-06.
  17. ^ {{Cite web |title=The Children’s Hospital Charity |url=https://www.tchc.org.uk/about-us/meet-the-team/trustees/%7C access-date=2025-05-05
  18. ^ {{Cite web |title=A Rare Cause |url=https://ararecause.org | access-date=2025-05-05
  19. ^ Thayyil, Sudhin; Sebire, Neil J; Chitty, Lyn S; Wade, Angie; Chong, Wk; Olsen, Oystein; Gunny, Roxana S; Offiah, Amaka C; Owens, Catherine M; Saunders, Dawn E; Scott, Rosemary J; Jones, Rod; Norman, Wendy; Addison, Shea; Bainbridge, Alan (2013-07-16). "Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study". The Lancet. 382 (9888): 223–233. doi:10.1016/S0140-6736(13)60134-8. PMID 23683720.
  20. ^ Offiah, A. C. (2006-11-01). "Acute osteomyelitis, septic arthritis and discitis: Differences between neonates and older children". European Journal of Radiology. Neonate Imaging. 60 (2): 221–232. doi:10.1016/j.ejrad.2006.07.016. ISSN 0720-048X. PMID 16971078.
  21. ^ Turnpenny, Peter D.; Alman, Ben; Cornier, Alberto S.; Giampietro, Philip F.; Offiah, Amaka; Tassy, Olivier; Pourquié, Olivier; Kusumi, Kenro; Dunwoodie, Sally (2007). "Abnormal vertebral segmentation and the notch signaling pathway in man". Developmental Dynamics. 236 (6): 1456–1474. doi:10.1002/dvdy.21182. ISSN 1097-0177. PMID 17497699.
  22. ^ Mercuri, Eugenio; Clements, Emma; Offiah, Amaka; Pichiecchio, Anna; Vasco, Gessica; Bianco, Flaviana; Berardinelli, Angela; Manzur, Adnan; Pane, Marika; Messina, Sonia; Gualandi, Francesca; Ricci, Enzo; Rutherford, Mary; Muntoni, Francesco (2010). "Muscle magnetic resonance imaging involvement in muscular dystrophies with rigidity of the spine". Annals of Neurology. 67 (2): 201–208. doi:10.1002/ana.21846. ISSN 1531-8249. PMID 20225280.
  23. ^ Bochukova, Elena; Schoenmakers, Nadia; Agostini, Maura; Schoenmakers, Erik; Rajanayagam, Odelia; Keogh, Julia M.; Henning, Elana; Reinemund, Jana; Gevers, Evelien; Sarri, Margarita; Downes, Kate; Offiah, Amaka; Albanese, Assunta; Halsall, David; Schwabe, John W. R. (2012-01-19). "A Mutation in the Thyroid Hormone Receptor Alpha Gene". New England Journal of Medicine. 366 (3): 243–249. doi:10.1056/NEJMoa1110296. ISSN 0028-4793. PMID 22168587.
  24. ^ Offiah, Amaka C.; Adamsbaum, Catherine; van Rijn, Rick R. (2014-10-07). "ESPR adopts British guidelines for imaging in suspected non-accidental injury as the European standard". Pediatric Radiology. 44: 1338. doi:10.1007/s00247-014-3153-3. ISSN 1432-1998. PMID 34494143.
  25. ^ Choudhary, Arabinda Kumar; Servaes, Sabah; Slovis, Thomas L.; Palusci, Vincent J.; Hedlund, Gary L.; Narang, Sandeep K.; Moreno, Joëlle Anne; Dias, Mark S.; Christian, Cindy W.; Nelson, Marvin D.; Silvera, V. Michelle; Palasis, Susan; Raissaki, Maria; Rossi, Andrea; Offiah, Amaka C. (2018). "Consensus statement on abusive head trauma in infants and young children". Pediatric Radiology. 48 (8): 1048–1065. doi:10.1007/s00247-018-4149-1. ISSN 0301-0449. PMID 29796797.
  26. ^ "Fifty years of Pediatric Radiology".
  27. ^ Javaid, Muhammad Kassim; Boyce, Alison; Appelman-Dijkstra, Natasha; Ong, Juling; Defabianis, Patrizia; Offiah, Amaka; Arundel, Paul; Shaw, Nick; Pos, Valter Dal; Underhil, Ann; Portero, Deanna; Heral, Lisa; Heegaard, Anne-Marie; Masi, Laura; Monsell, Fergal (2019-06-13). "Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium". Orphanet Journal of Rare Diseases. 14 (1): 139. doi:10.1186/s13023-019-1102-9. ISSN 1750-1172. PMC 6567644. PMID 31196103.
  28. ^ Savarirayan, Ravi; Ireland, Penny; Irving, Melita; Thompson, Dominic; Alves, Ines; Baratela, Wagner A.R.; Betts, James; Bober, Michael B.; Boero, Silvio; Briddell, Jenna; Campbell, Jeffrey; Campeau, Philippe M.; Carl-Innig, Patricia; Cheung, Moira S.; Cobourne, Martyn; Cormier-Daire, Valerie; Deladure-Molla, Muriel; del Pino, Mariana; Elphick, Heather; Fano, Virgina; Fauroux, Brigitte; Gibbins, Jonathan; Groves, Mari L.; Hagenas, Lars; Hannon, Therese; Hoover-Fong, Julie; Kaisermann, Morrys; Leiva-Gea, Antonio; Llerna, Juan; Mackenzie, William; Martin, Kenneth; Mazzoleni, Fabio; McDonnell, Sharon; Meazzini, Maria C.; Milerad, Josef; Mohnike, Klaus; Mortier, Geert R.; Offiah, Amaka; Ozono, Keiichi; Phillips III, John A.; Powell, Steven; Prasad, Yosha; Raggio, Cathleen; Rosselli, Pablo; Rossiter, Judith; Selicorni, Angelo; Sessa, Marco; Theroux, Mary; Thomas, Matthew; Trespedi, Laura; Tunkel, David; Wallis, Colin; Wright, Michael; Yasui, Natsuo; Fredwall, Svein O. (2021-11-26). "International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia". Nature Reviews Endocrinology. 18: 173–189. doi:10.1038/s41574-021-00595-x. ISSN 1759-5037. PMID 34837063.
  29. ^ "Previous Winners - British Institute of Radiology". www.bir.org.uk. Retrieved 2025-02-06.
  30. ^ Hawkes, Nigel (2015-04-08). "Imaging team of the year". BMJ. 350: h1747. doi:10.1136/bmj.h1747. ISSN 1756-1833. PMID 25854263.
  31. ^ "Prog Annual meeting June 9 – ESPR 2022". 2025-05-04.
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