Flumioxazin

Flumioxazin
Names
	IUPAC name 2-(7-Fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione
	Other names Flumioxazine
Identifiers
CAS Number	103361-09-7;
3D model (JSmol)	Interactive image;
PubChem CID	92425;
	SMILES C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F;
Properties
Chemical formula	C19H15FN2O4
Molar mass	354.337 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Flumioxazin is an herbicide used for control of broadleaf weeds in agricultural areas.^[1] It is also used to control aquatic plants. In granular form it is used to control of submerged plants, and as a direct foliar application it is used to control emergent and floating-leaf plants.^[2] It can also be used to control some filamentous algae.^[2]

Flumioxazin is an inhibitor of the enzyme protoporphyrinogen oxidase which then interferes with the plant's chlorophyll production.^[3]

References

^ "Flumioxazin: Environmental Fate and Ecological Risk Assessment" (PDF). United States Environmental Protection Agency.
^ ^a ^b "Flumioxazin Chemical Fact Sheet" (PDF). Wisconsin Department of Natural Resources. 2012.
^ Iwashita, Katsumasa; Hosokawa, Yoshinori; Ihara, Ryo; Miyamoto, Taiki; Otani, Mitsuhiro; Abe, Jun; Asano, Koji; Mercier, Odile; Miyata, Kaori; Barlow, Susan (2022). "Flumioxazin, a PPO inhibitor: A weight-of-evidence consideration of its mode of action as a developmental toxicant in the rat and its relevance to humans". Toxicology. 472. Bibcode:2022Toxgy.47253160I. doi:10.1016/j.tox.2022.153160. PMID 35367320.

[1] "Flumioxazin: Environmental Fate and Ecological Risk Assessment" (PDF). United States Environmental Protection Agency.

[noaa-2] "Flumioxazin Chemical Fact Sheet" (PDF). Wisconsin Department of Natural Resources. 2012.

[3] Iwashita, Katsumasa; Hosokawa, Yoshinori; Ihara, Ryo; Miyamoto, Taiki; Otani, Mitsuhiro; Abe, Jun; Asano, Koji; Mercier, Odile; Miyata, Kaori; Barlow, Susan (2022). "Flumioxazin, a PPO inhibitor: A weight-of-evidence consideration of its mode of action as a developmental toxicant in the rat and its relevance to humans". Toxicology. 472. Bibcode:2022Toxgy.47253160I. doi:10.1016/j.tox.2022.153160. PMID 35367320.

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