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User:Reph-415

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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Hi
I have tons of sexual intercourse all the time.[citation needed]

to do

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  • Iboluteine (ibogaine pseudoindoxyl) - An ibogaine oxydation product, analogous to the poorly studied opioid mitragynine pseudoindoxyl. Iboluteine and related metabolites possibly contribute to iboga's therapeutic effects. UPDATE : Unfortunately, research about iboga and its alkaloids has come to a crawling stop because of insane anti-drug propaganda from france and north america.

List of non-hallucinogenic 5-HT2A agonists

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Tryptamines

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Mescaline analogs

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Others

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List of atypical monoamine transporter ligands

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There are many similar and/or contradicting hypotheses about monoamine transporter binding sites, here are some of them.

SERT

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4-TFMMC, an SERT negative allosteric modulator
Compound 7a, an SERT positive allosteric modulator

NET

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  • NET NAM / "partial releaser" : αET (Emax ~ 75%) [4]

DAT

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Others

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RTI-4793-14
  • Selegiline, (-)-PPAP, others : monoaminergic activity enhancers (MAEs). Selegiline enhances transporter-mediated dopamine release independently of MAO-B inhibition. It's unclear whether or not this mechanism of action is distinct from MAT allosteric modulation.
  • PCP and RTI-4793-14 bind to PCP site 2. Binding causes monoamine reuptake inhibition. This binding site is distinct from typical reuptake inhibitor/substrate binding sites. Possibly a set of 3 allosteric modulator sites (one on each MAT).