Aldose 1-dehydrogenase
| aldose 1-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.121 | ||||||||
| CAS no. | 9076-61-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an aldose 1-dehydrogenase (EC 1.1.1.121) is an enzyme that catalyzes the chemical reaction
- D-aldose + NAD+ D-aldonolactone + NADH + H+
Thus, the two substrates of this enzyme are D-aldose and NAD+, whereas its 3 products are D-aldonolactone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-aldose:NAD+ 1-oxidoreductase. Other names in common use include aldose dehydrogenase, and dehydrogenase, D-aldohexose.
References
[edit]- Cline AL, Hu AS (1965). "The isolation of three sugar dehydrogenases from a psuedomonad [sic]". J. Biol. Chem. 240 (11): 4488–92. PMID 5845847.
- Cline AL, Hu AS (1965). "Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4493–7. PMID 5845848.
- Cline AL, Hu AS (1965). "Some physical properties of three sugar dehydrogenases from a pseudomonad". J. Biol. Chem. 240 (11): 4498–502. PMID 5845849.
