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Glucose-1-phosphatase

From Wikipedia, the free encyclopedia
glucose-1-phosphatase
Identifiers
EC no.3.1.3.10
CAS no.9001-38-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme glucose-1-phosphatase (EC 3.1.3.10) catalyzes the reaction

α-D-glucose 1-phosphate + H2O D-glucose + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is α-D-glucose-1-phosphate phosphohydrolase. This enzyme participates in glycolysis and gluconeogenesis.

Structural studies

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As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1NT4.

References

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  • Faulkner P (August 1955). "A hexose-1-phosphatase in silkworm blood". The Biochemical Journal. 60 (4): 590–6. doi:10.1042/bj0600590. PMC 1216157. PMID 13249953.
  • Turner DH, Turner JF (March 1960). "The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds". The Biochemical Journal. 74 (3): 486–91. doi:10.1042/bj0740486. PMC 1204246. PMID 13839934.